NAD+

Overview of NAD+ in Research

Nicotinamide Adenine Dinucleotide (NAD+) is a vital coenzyme found in all living cells and is a cornerstone of cellular metabolism research. In laboratory settings, NAD+ exists as a dinucleotide, consisting of two nucleotides joined through their phosphate groups: one containing an adenine base and the other containing nicotinamide. This molecule serves as a critical electron carrier in redox reactions, transitioning between its oxidized form (NAD+) and its reduced form (NADH). Research into NAD+ focuses heavily on its role as a substrate for various enzymes, including sirtuins and poly(ADP-ribose) polymerases (PARPs), which are central to genomic stability and cellular signaling pathways.

In biochemistry and molecular biology experiments, NAD+ is frequently studied to understand the mechanisms of mitochondrial function and energy homeostasis. As a fundamental component of the electron transport chain, its presence is mandatory for the production of adenosine triphosphate (ATP) in cellular models. Researchers utilize NAD+ to observe metabolic flux, enzymatic kinetics, and the complex interactions within the metabolic landscape of diverse cell lines. The chemical structure and stability of NAD+ make it a primary subject for investigation into cellular aging, DNA repair mechanisms, and systemic metabolic regulation in controlled environment studies.

Specifications

Our NAD+ is manufactured to meet the highest standards for laboratory consistency and reliability. Each batch undergoes rigorous validation to ensure experimental reproducibility.

• Purity: 99%+ as determined by analytical testing.
• Testing Protocols: Third-party HPLC (High-Performance Liquid Chromatography) and MS (Mass Spectrometry) verified for identity and purity.
• Documentation: A Certificate of Analysis (COA) is available for every batch to confirm chemical specifications.
• Format: Provided as a lyophilized (freeze-dried) powder to maintain structural integrity during transit.
• Available Sizes: 500 MG and 1000 MG vials.

Handling and Storage

Proper handling of NAD+ is essential to prevent degradation and ensure the accuracy of experimental data. The lyophilized powder is highly stable but sensitive to moisture and extreme temperature fluctuations. Upon receipt, the vials should be stored in a controlled environment. For long-term preservation, it is recommended to store the powder at -20°C. If the material is intended for use within a shorter timeframe, refrigeration at 2°C to 8°C is generally sufficient.

Reconstitution is a standard laboratory procedure typically performed using bacteriostatic water or a sterile saline buffer, depending on the requirements of the specific research protocol. Once reconstituted, the stability of the solution decreases significantly compared to the lyophilized form. Researchers should prepare aliquots of the solution to avoid repeated freeze-thaw cycles, which can lead to the hydrolysis of the pyrophosphate bond. Reconstituted NAD+ should be stored at -20°C or -80°C and used within a strictly defined period to ensure the integrity of the coenzyme during in-vitro applications.

Buy NAD+ Online

When you choose to source your research materials from our laboratory supply, you are guaranteed a product that meets exacting purity standards. We understand the importance of timely data acquisition, which is why we prioritize efficient processing for all orders. Our NAD+ is stocked and ready for immediate dispatch from our domestic facilities.

We provide fast USA shipping to ensure that your laboratory receives the necessary compounds without unnecessary delays. Every order is packaged using discreet, professional materials to maintain the privacy and security of your research procurement. By maintaining a robust supply chain, we ensure that researchers have consistent access to high-purity NAD+ in both 500 MG and 1000 MG formats, supporting large-scale studies and pilot projects alike.

Research Use Only

Compliance Notice: The NAD+ provided is strictly for laboratory research purposes only. This product is not a drug, food, cosmetic, or dietary supplement. It is not intended for human or veterinary consumption, and any form of administration to humans or animals is strictly prohibited. This compound is intended solely for use by qualified professionals in an in-vitro laboratory setting. The purchaser assumes all responsibility for the handling, storage, and application of this chemical within the legal and safety frameworks of their jurisdiction. This product is not designed to diagnose, treat, cure, or prevent any disease or medical condition.